Mixed carotenoids include nutrients such as beta-carotene, lutein, lycopene, and others. Found in many fruits and vegetables, these nutrients are potent anti-oxidants; they protect DNA from oxidative damage which may lead to potentially cancer-causing mutations.1
A deficiency in carotenoids in the body can play a role in development of cervical dysplasia and HPV.2 Having higher levels is correlated with having a lower risk of HPV.3
A study of 235 women done in 2006 4 compared healthy women to those with cervical cancer. It was found that women with cervical cancer had much lower levels of carotenoids in their blood. Carotenoids appear to be protective against HPV.
Making sure that you get an adequate amount of mixed carotenoids is very important to help prevent cervical dysplasia. It is also important to ensure that carotenoids are mixed (a variety of different carotenoids together), since taking a high dose of an individual carotene, especially beta carotene, may have negative effects. 5
1 Davidson SE, West CM, Hunter RD. Lack of association between in vitro clonogenic
growth of human cervical carcinoma and tumour stage, differentiation, patient age,
host cell infiltration or patient survival. Int J Cancer. 1992 Jan 2;50(1):10-4.
2 Palan PR, Mikhail MS, Basu J, Romney SL. Beta-carotene levels in exfoliated
cervicovaginal epithelial cells in cervical intraepithelial neoplasia and cervical cancer.
Am J Obstet Gynecol. 1992 Dec;167(6):1899-903.
3 Nagata C, Shimizu H, Yoshikawa H, Noda K, Nozawa S, Yajima A, Sekiya S,
Sugimori H, Hirai Y, Kanazawa K, Sugase M, Kawana T. Serum carotenoids and
vitamins and risk of cervical dysplasia from a case-control study in Japan. Br J
Cancer. 1999 Dec;81(7):1234-7.
4 Palan PR, Mikhail MS, Goldberg GL, Basu J, Runowicz CD, Romney SL. Plasma
levels of beta-carotene, lycopene, canthaxanthin, retinol, and alpha- and tautocopherol
in cervical intraepithelial neoplasia and cancer. Clin Cancer Res. 1996
5. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330:1029-1035.